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Symptoms and Signs – Differential Diagnosis of Mitral regurgitation
Chordal rupture and floppy mitral valve associated with connective tissue diseases (pseudoxanthoma elasticum, osteogenesis imperfecta, Ehlers-Danlos syndrome, Marfan's syndrome, SLE}
Functional mitral regurgitation: secondary to left ventricular dilatation
Infective endocarditis
Mitra! valve prolapse
Papillary muscle rupture (after Ml) or dysfunction (ischaemic heart disease/ cardiomyopathy}
Rheumatic heart disease


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Symptoms and Signs – Differential Diagnosis of Lipodystrophy
Associated with membranoproliferative glomerulonephritis (type II)
Congenital
HIV drugs: protease inhibitors
Idiopathic
Injection, e.g. insulin
Local
Panniculitis
Partial
Pressure



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Symptoms and Signs – Differential Diagnosis of Liver function tests
Raised AST (SGOT)
Hepatocyte damage
Haemolysis
Myocardial infarction
Skeletal muscle damage
Raised ALT (SGPT),
Hepatocyte damage
Shock
Raised ALP,
Liver disease: cholestasis
Bone disease (i osteoblastic activity): growth in adolescence, healing fracture,
Paget's disease of bone, osteomalacia, bone metastases, hyperparathyroidism,
renal failure
Placenta: pregnancy
Small intestinal disease


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