Pharmacology - Pyrazinamide
Pharmacology - Pyrazinamide Action of Pyrazinamide: Bactericidal against actively dividing mycobacteria within cells. A lot happens in the first few months. Action Process Turns into pyrazinoic acid, which stops Mycobacterium tuberculosis from transpor
Pharmacology - Ethambutol
Pharmacology - Ethambutol Ethambutol is a bacteriostatic agent that inhibits the growth of tuberculosis bacilli. Action Technique As tuberculosis bacilli divide, it prevents them from constructing their cell wall. When taken orally, it has the potentia
Pharmacology - Zidovudine
Pharmacology - Zidovudine The activity of zidovudine is to block the HIV virus's reverse transcriptase. Mode of Action The enzymes in the host cell phosphorylate zidovudine to make zidovudine trisphosphate, which blocks the viral DNA manufacturing proc
Pharmacology - Nevirapine
Pharmacology - Nevirapine How Nevirapine Works: It stops the AIDS virus's HIV reverse transcriptase from working. It works on HIV-1 but not on HIV-2. How it works It binds to the virus reverse transcriptase enzyme and breaks it down. Given by mouth; th
Pharmacology - Saquinavir
Pharmacology - Saquinavir This reversible inhibitor blocks the viral-specific protease, which is responsible for cleaving precursor viral proteins during budding and assembly to produce the structural and functional proteins of newly formed virions. Ac
Pharmacology - Enfuvirtide
Pharmacology - Enfuvirtide Inhibiting HIV entrance into host cells is the action of enfuvirtide. Functions by attaching to an HIV envelope subunit, which in turn blocks the virus from infecting the mammalian cell by preventing it from fusing with the ta
Pharmacology - Aciclovir
Pharmacology - Aciclovir Aciclovir works by blocking the production of viral nucleic acids. Mode of Action Acyclovir triphosphate is produced when viral and host cell kinases convert aciclovir to a form that inhibits viral DNA polymerase. When admini
Pharmacology - Ganciclovir
Pharmacology - Ganciclovir Ganciclovir works by blocking the production of viral nucleic acids. Mode of Action Kinases in both the virus and the host cell convert it to ganciclovir triphosphate, which inhibits viral DNA replication by competing with gu
Pharmacology - Oseltamivir
Pharmacology - Oseltamivir Oseltamivir works by stopping viruses from replicating themselves. How it works Stops neuraminidase from working, which is needed for virion release. Given by mouth within 48 hours of the start of symptoms for post-exposure p
Pharmacology - Palivizumab
Pharmacology - Palivizumab One of palivizumab's functions is to prevent viruses from infecting host cells. Effect Mechanism Respiratory syncytial virus surface protein is targeted by this humanized monoclonal antibody. Given by injecting it into the mus
