Pathology - Polycythemia Vera Polycythemia Vera is a medical condition characterized by an abnormal increase in the number of red blood cells in the body. Myeloproliferative disorder is a condition where there is abnormal growth of blood cells. In 95%

Pathology - Myelofibrosis with Myeloid Metaplasia Fibroblastic proliferation in the bone occurs as a consequence of elevated secretion of PDGF and TGF-B. Study of the nature and causes of diseases. Bone marrow: The bone marrow cavity is replaced by fibr

Pathology - Hodgkin lymphoma The cause is currently unknown, but EB infection has been suggested as a possible factor. The typical occurrence is in a 20-year-old male, however Hodgkin lymphoma has a dual age distribution pattern, with a high incidence bet

Pathology - Non-Hodgkin lymphoma Chromosomal translocations are genetic abnormalities that occur in some types of lymphomas. In Burkitt lymphoma, a specific translocation called t(8;14) leads to the overexpression of the c-myc gene. In follicular lymphoma

Pathology - Multiple Myeloma A tumor cell originates from the rapid growth of a single type of plasma cells, known as monoclonal plasma cells, that are responsible for producing immunoglobulin G (IgG). Most prevalent among individuals over the age of 60.

Pathology - Waldenstrom Macroglobulinemia The hyperviscosity syndrome is mostly linked to the presence of IgM-producing plasmacytic lymphocytes, which are a combination of plasma cells and B lymphocytes. Most commonly observed in males over the age of 30.

Pathology - Idiopathic and Thrombotic Thrombocytopenic Purpura Idiopathic thrombocytopenic purpura (ITP) is a condition where platelets are coated with antiplatelet IgG antibodies, causing them to be engulfed by macrophages in the spleen. May be linked t

Pathology - Hemophilias A and B Hemophilias A and B are genetic disorders characterized by a deficiency in clotting factors VIII and IX, respectively. Hemophilia A is an X-linked recessive condition characterized by a lack of factor VIII. Hemophilia B is

Dermatology - Hairy Cell Leukemia Primarily manifests in males of middle age. Study of the nature and causes of diseases. Bone marrow: Presence of hairy cells (B cells with hairlike projections) that exhibit positive staining for TRAP, resulting in inte

Pathology - Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia is a type of cancer that affects the white blood cells. Linked to genetic disorders involving an extra copy of chromosome 12, deletions of chromosome 13g, and deletions of chromosome